Leishmaniasis

Leishmaniasis is caused by the intracellular protozoa Leishmania, usually being spread by sand flies. Cutaneous, mucocutaneous leishmaniasis and visceral forms are seen

Cutaneous leishmaniasis

caused by Leishmania tropica or Leishmania mexicana
crusted lesion at site of bite
may be underlying ulcer

Mucocutaneous leishmaniasis

caused by Leishmania braziliensis
skin lesions may spread to involve mucosae of nose, pharynx etc

Visceral leishmaniasis (kala-azar)

mostly caused by Leishmania donovani
occurs in the Mediterranean, Asia, South America, Africa
fever, sweats, rigors
massive splenomegaly. hepatomegaly
poor appetite*, weight loss
grey skin - 'kala-azar' means black sickness
pancytopaenia secondary to hypersplenism

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